Apache is slower, heavier and more complicated to setup than Nginx. But it’s also much more famous:
An Apache setup is still much more robust and secure than an easy installation.
Une installation apache est aussi beaucoup plus solide et sécurisé qu’une installation facile. You’ll benefit from having:
The modern Web Python servers all work the same way, following an norm for interfacing: WSGI.
This is the most performante solution, and the best to use. But it will require the setup of the Apache module mod_wsgi. If you don’t know how to do this, or if you can’t do it (E.G: your hosting won’t let you), you need to go for the CGI setup.
This setup is considered as slow, but you will still benefit from Apache robustness.