diff --git a/telebot/__init__.py b/telebot/__init__.py
index a102964..0458cc3 100644
--- a/telebot/__init__.py
+++ b/telebot/__init__.py
@@ -4564,6 +4564,23 @@ class TeleBot:
         result = apihelper.get_custom_emoji_stickers(self.token, custom_emoji_ids)
         return [types.Sticker.de_json(sticker) for sticker in result]
     
+    def set_sticker_keywords(self, sticker: str, keywords: List[str]=None) -> bool:
+        """
+        Use this method to change search keywords assigned to a regular or custom emoji sticker.
+        The sticker must belong to a sticker set created by the bot.
+        Returns True on success.
+
+        :param sticker: File identifier of the sticker.
+        :type sticker: :obj:`str`
+
+        :param keywords: A JSON-serialized list of 0-20 search keywords for the sticker with total length of up to 64 characters
+        :type keywords: :obj:`list` of :obj:`str`
+
+        :return: On success, True is returned.
+        :rtype: :obj:`bool`
+        """
+        return apihelper.set_sticker_keywords(self.token, sticker, keywords)
+    
 
     def set_custom_emoji_sticker_set_thumbnail(self, name: str, custom_emoji_id: Optional[str]=None) -> bool:
         """
diff --git a/telebot/apihelper.py b/telebot/apihelper.py
index 8612532..c48df05 100644
--- a/telebot/apihelper.py
+++ b/telebot/apihelper.py
@@ -1620,6 +1620,14 @@ def get_sticker_set(token, name):
 def get_custom_emoji_stickers(token, custom_emoji_ids):
     method_url = r'getCustomEmojiStickers'
     return _make_request(token, method_url, params={'custom_emoji_ids': json.dumps(custom_emoji_ids)})
+
+def set_sticker_keywords(token, sticker, keywords=None):
+    method_url = 'setStickerKeywords'
+    payload = {'sticker': sticker}
+    if keywords:
+        payload['keywords'] = json.dumps(keywords)
+    return _make_request(token, method_url, params=payload, method='post')
+
     
 def upload_sticker_file(token, user_id, sticker, sticker_format):
     method_url = 'uploadStickerFile'
diff --git a/telebot/async_telebot.py b/telebot/async_telebot.py
index b50e987..4e8ecdc 100644
--- a/telebot/async_telebot.py
+++ b/telebot/async_telebot.py
@@ -5412,6 +5412,23 @@ class AsyncTeleBot:
         """
         result = await asyncio_helper.get_sticker_set(self.token, name)
         return types.StickerSet.de_json(result)
+    
+    async def set_sticker_keywords(self, sticker: str, keywords: List[str]=None) -> bool:
+        """
+        Use this method to change search keywords assigned to a regular or custom emoji sticker.
+        The sticker must belong to a sticker set created by the bot.
+        Returns True on success.
+
+        :param sticker: File identifier of the sticker.
+        :type sticker: :obj:`str`
+
+        :param keywords: A JSON-serialized list of 0-20 search keywords for the sticker with total length of up to 64 characters
+        :type keywords: :obj:`list` of :obj:`str`
+
+        :return: On success, True is returned.
+        :rtype: :obj:`bool`
+        """
+        return await asyncio_helper.set_sticker_keywords(self.token, sticker, keywords)
 
     async def get_custom_emoji_stickers(self, custom_emoji_ids: List[str]) -> List[types.Sticker]:
         """
diff --git a/telebot/asyncio_helper.py b/telebot/asyncio_helper.py
index 6268fff..d6f3774 100644
--- a/telebot/asyncio_helper.py
+++ b/telebot/asyncio_helper.py
@@ -1608,6 +1608,14 @@ async def get_custom_emoji_stickers(token, custom_emoji_ids):
     method_url = r'getCustomEmojiStickers'
     return await _process_request(token, method_url, params={'custom_emoji_ids': json.dumps(custom_emoji_ids)})
 
+async def set_sticker_keywords(token, sticker, keywords=None):
+    method_url = 'setStickerKeywords'
+    payload = {'sticker': sticker}
+    if keywords:
+        payload['keywords'] = json.dumps(keywords)
+        
+    return await _process_request(token, method_url, params=payload, method='post')
+
 async def upload_sticker_file(token, user_id, sticker, sticker_format):
     method_url = 'uploadStickerFile'
     payload = {'user_id': user_id, 'sticker_format': sticker_format}